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[27 Jun 2022 | No comments | 94 views ]
CRINET: Competing endogenous RNA (ceRNA) interactions inference

CRINET: A computational tool to infer genome-wide competing endogenous RNA (ceRNA) interactions

To understand driving biological factors for complex diseases like cancer, regulatory circuity of genes needs to be discovered. Recently, a new gene regulation mechanism called competing endogenous RNA (ceRNA) interactions has been discovered. Certain genes targeted by common microRNAs (miRNAs) “compete” for these miRNAs, thereby regulate each other by making others free from miRNA regulation. Several computational tools have been published to infer ceRNA networks. In most existing tools, …

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